Author

Yongchang Chen

Kunming University of Science and TechnologyORCID 0000-0002-3856-3576Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 2 Organism:non-human primate· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

Weizhi JiiD· 3 shared Jiaojian WangiD· 2 shared Wenjie Sun· 2 shared Alexander GoedeliD· 1 shared Chenyang Si· 1 shared Chikai ZhouiD· 1 shared Chong Chang· 1 shared Chu Chu· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersNeuroscience

Weizhi JiORCID

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Author profile →

3 papers

Recent·Most cited

Repetitive transcranial magnetic stimulation targeting motor cortical region induces cell-type-specific transcriptional reprogramming and behavioral recovery in non-human primate model of Rett syndrome

Wei Li, Wenjie Sun, Jing Su, Futing Yang, Xia Qiu, Yan Zhuo, Zeyuan Yang, Zhengbo Wang, Zhigang Chen, Tianzhuang Huang, Hong Wang, Haoyang Xing, Weizhi Ji, Ti‐Fei Yuan, Yongchang Chen, Jiaojian Wang

This study shows that rTMS targeting the motor cortex in a non-human primate model of Rett syndrome improves behavioral outcomes and induces cell-type-specific transcriptional changes.

bioRxiv · Oct 26, 2026 · PreprintNeuroscience

Elimination of intramuscular immunoglobulin accumulation alleviates Duchenne Muscular Dystrophy

Li Zhang, Wenting Guo, Mei Huang, Z Y Liang, Enni Zhu, Geng Li, Chong Chang, X S Guo, Wenjie Sun, Jia Li, J S Liu, Han Qiu, L C Zhu, Shuaiwei Ren, Raoxian Bai, , Xing Chang

This study identifies IgG accumulation in dystrophin-deficient muscle as a driver of DMD progression and shows that B cell depletion reduces it, offering a potential therapeutic strategy.

bioRxiv · Feb 12, 2026 · PreprintImmunology

Amnion signals are essential for mesoderm formation in primates

Ran Yang, Alexander Goedel, Yu Kang, Chenyang Si, Chu Chu, Yi Zheng, Zhenzhen Chen, Peter J. Gruber, Yao Xiao, Chikai Zhou, Nevin Witman, Elif Eroğlu, Chuen-Yan Leung, Yongchang Chen, Jianping Fu, , Kenneth R. Chien

The paper identifies ISL1's critical role in primate mesoderm formation through a transcriptional atlas and CRISPR experiments in non-human primates.

Nature Communications · Aug 26, 2021Peer-reviewedDevelopmental Biology