Pierre E. Thibeault

This study shows that liver-specific loss of ARGLU1 in mice prevents diet-induced obesity without affecting food intake, locomotion, or energy expenditure, due to reduced lipid absorption and altered bile acid metabolism.

This study investigates how the 8th-helix and carboxyl terminal tail of PAR4 regulate signaling by affecting G protein activation, β-arrestin recruitment, and interactions with regulatory proteins.