Rithwik Ramachandran

This study investigates how second-scale neural dynamics in CRH neurons translate stress signals into sustained hormonal outputs, showing firing rate over seconds determines CRH release.

This study investigates how the 8th-helix and carboxyl terminal tail of PAR4 regulate signaling by affecting G protein activation, β-arrestin recruitment, and interactions with regulatory proteins.

The paper uses AlphaFold to predict and analyze 3D structures of aGPCRs in active and inactive states, revealing insights into their activation mechanisms and conformational changes.