Author

Sergio P. Acebrón

IkerbasqueORCID 0000-0002-7694-2497Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Gislene PereiraiD· 2 shared Alexander Haas· 1 shared Ana J. García‐SáeziD· 1 shared Anchel De Jaime-SogueroiD· 1 shared Anja Ciprinidis· 1 shared Anna Sophia JauchiD· 1 shared Ayushi Branushali· 1 shared Cheng YuaniD· 1 shared

Activity by Year

2025-2025 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersCell Biology

Gislene PereiraORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Long-term prevention of aneuploidy in human pluripotent stem cells by fine-tuning GSK3 activity

Anchel De Jaime-Soguero, Mírian Romitti, Sabine Costagliola, Anna Sophia Jauch, G. Vilangappurath, Karl Willert, F. Foijer, S.P. Acebrón

This study shows that low-dose GSK3 inhibitors prevent aneuploidy in hPSCs by reducing mitotic DNA synthesis and ultra-fine chromosome bridges during long-term culture.

bioRxiv · Oct 27, 2025 · PreprintCell Biology

Wnt10b signaling regulates replication stress-induced chromosomal instability in human cancer

Alexander Haas, Friederike Wenz, Janina Hattemer, Janine Wesslowski, Gary R. Davidson, Oksana Voloshanenko, Michael Boutros, Sergio P. Acebrón, Holger Bastians

This study shows Wnt10b signaling prevents replication stress-induced chromosomal instability in cancer cells by suppressing microtubule dynamics and chromosome missegregation.

Life Science Alliance · Aug 22, 2025Peer-reviewedCell Biology

Spatio-temporal analysis of the innate immune response to cytoplasmic dsDNA using a novel cGAMP biosensor

Steve Smarduch, Sergio David Moreno-Velásquez, Doroteja Ilic, Shashank Dadsena, Ryan Morant, Anja Ciprinidis, Gislene Pereira, Marco Binder, Ana J. García‐Sáez, Sergio P. Acebrón

The paper develops a fluorescent cGAMP biosensor to monitor cGAS-STING signaling dynamics in real-time and across different cellular contexts.

The EMBO Journal · Feb 21, 2025Peer-reviewedCell Biology

Wnt/LRP6 signaling imbalance impairs ciliogenesis in human retina epithelial cells

Cheng Yuan, Ayushi Branushali, Matias Simons, Sergio P. Acebrón, Gislene Pereira

This study shows that both excessive and insufficient Wnt signaling disrupt ciliogenesis in human retinal epithelial cells, highlighting the interplay between Wnt and mTOR signaling.

bioRxiv · Jan 10, 2025 · PreprintCell Biology