Abhishek Dey

Pan-Viral Conformational Landscapes of Frameshifting Elements Reveal Length-Dependent Plasticity and Antisense-Driven Structural Reprogramming

The paper analyzes the conformational landscapes of frameshifting elements (FSEs) across multiple viruses, revealing length-dependent plasticity and antisense-driven structural changes.

Interactions of Natural Compounds and Biomolecules with Hepatitis C Virus RNA Untranslated Regions: Exploring Structural Modifications to Advance Pathogenesis Understanding and Antiviral Strategy Design

This study examines interactions of HCV UTRs with miRNAs, phytochemicals, and proteins, revealing structural changes and novel interactors that may influence viral pathogenesis and antiviral strategies.

An intricate balancing act: Upstream and downstream frameshift co-regulatory elements

The paper investigates the RNA structures and interactions of the 5' and 3' regions of the SARS-CoV-2 frameshifting element, revealing their co-regulatory roles and implications for therapeutic interventions.

Abolished frameshifting for predicted structure-stabilizing SARS-CoV-2 mutants: Implications to alternative conformations and their statistical structural analyses

The paper shows that predicted SARS-CoV-2 FSE mutants abolish frameshifting and suppress structural transitions, highlighting the role of alternative conformations in ribosomal transitions.

Comprehensive structural and interactome analysis reveals novel interactions and protein binding sites in miR-675: a non-coding RNA critically involved in multiple diseases

This study identifies the structure and interactome of miR-675, revealing novel protein binding sites and interactions that may serve as therapeutic targets for diseases.

Quantitative prediction of variant effects on alternative splicing using endogenous pre-messenger RNA structure probing

The paper predicts variant effects on alternative splicing using structural probing data and a computational framework, achieving 90% accuracy for splice-altering variants.

The RNA Structurome in the Asexual Blood Stages of Malaria Pathogen Plasmodium falciparum

This study measures RNA secondary structures in Plasmodium falciparum during asexual development, finding that ~71% of structured RNAs are protein-coding and that structural content correlates with translation efficiency.