Author

Michael R. Strickland

Washington University in St. LouisORCID 0000-0002-3899-5651Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

David M. HoltzmaniD· 2 shared Adrian Higginbottom· 1 shared Agnieszka N. UrbanekiD· 1 shared Anil G. CashikariD· 1 shared Anna OlerinyovaiD· 1 shared Damian C. CrowtheriD· 1 shared Danira Toral-RíosiD· 1 shared David KlenermaniD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

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10 top collaborators · 31 mutual co-author links

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2 shared papersNeuroscience

David M. HoltzmanORCID

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2 papers

Recent·Most cited

NeuroscienceNature CommunicationsPeer-reviewedJun 1, 2024

Co-aggregation with Apolipoprotein E modulates the function of Amyloid-β in Alzheimer's disease

Zengjie Xia, Emily E. Prescott, Agnieszka N. Urbanek…·Suman De

The paper shows that apoE isoforms modulate Aβ aggregation, clearance, and toxicity in Alzheimer's disease, with implications for therapeutic strategies.

63 citationstop 1%

humanexperimental assay

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NeurosciencebioRxivPreprintSep 8, 2023

Microglial 25-hydroxycholesterol mediates neuroinflammation and neurodegeneration ina tauopathy mouse model

Danira Toral-Ríos, Justin M. Long, Jason D. Ulrich…·Steven M. Paul

This study shows that Ch25h/25HC promotes neuroinflammation and neurodegeneration in a tauopathy mouse model by enhancing proinflammatory signaling and impairing sterol synthesis.

DOI 10.1101/2023.09.08.556884

mousebulk RNA-seq

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