Author

Preston N. Samowitz

Scripps Research InstituteORCID 0000-0002-3940-303XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:perturbation response prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Courtney A. MilleriD· 2 shared Gavin RumbaughiD· 2 shared László RadnaiiD· 2 shared Alice LongiD· 1 shared Austin W. EdwardsiD· 1 shared Cameron J. DouglasiD· 1 shared Camilo J. RojasiD· 1 shared Carolyn BradleyiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersNeuroscience

Courtney A. MillerORCID

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2 papers

Recent·Most cited

NeuroscienceNature CommunicationsPeer-reviewedDec 9, 2025

The Endo-GeneScreen Platform Identifies Drug-Like Probes that Regulate Endogenous Protein Levels within Physiological Contexts

Preston N. Samowitz, László Radnai, Thomas Vaissière…·Gavin Rumbaugh

The paper introduces Endo-GeneScreen, a platform that identifies small molecules regulating endogenous protein levels, and demonstrates its application in finding probes for Syngap1-related neurodevelopmental disorder.

DOI 10.1038/s41467-025-65971-x

humanproteomics

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Molecular BiologybioRxivPreprintMar 13, 2025

Mesoscale proximity labeling to study macro changes to chromatin occupancy

Cameron J. Douglas, Preston N. Samowitz, Feifei Tong…·Ciaran P. Seath

The paper introduces MesoMap, a mesoscale proximity labeling method to study chromatin occupancy changes, showing how HDAC inhibitors and the drug SR-1815 affect gene expression.

4 citations

humanChIP-seq

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