Radical fringe facilitates NOTCH1 and JAG1 cis interactions to sustain Hematopoietic stem cell fate
Roshana Thambyrajah, María Maqueda, Wen Hao Neo, Kathleen J. Imbach, Yolanda Guillén, Daniela Grases, Muhammad Zaki Hidayatullah Fadlullah, Stefano Gambera, Francesca Matteini, Xiaonan Wang, Fernando J. Calero‐Nieto, Manel Esteller, Maria Carolina Florian, Eduard Porta‐Pardo, Rui Benedito, , Anna Bigas
The paper identifies NOTCH1-JAG1 cis interactions regulated by RADICAL FRINGE that maintain hematopoietic stem cell fate during development.
bioRxiv · Apr 19, 2023 · PreprintDevelopmental Biology