Pharmacology & ToxicologybioRxivPreprint
A Novel Hydrogen Polysulfide Donor Alleviates Neuropathic Pain by Enhancing A-Type Potassium Currents via LIMK1-Cofilin Mediated Interaction between Filamin A and Kv4.2
Ting Kang, Jierui Yan, Shirong Lai…·Bowen Ke
This paper develops a novel H2S2 donor, HPD1, which alleviates neuropathic pain by enhancing A-type potassium currents through a LIMK1-cofilin-Filamin A-Kv4.2 mechanism.
DOI 10.64898/2026.05.25.727751