Cancer BiologybioRxivPreprint
An oncolytic adenovirus armed with anticancer prodrug-activating enzyme offers enhanced tumor killing and antitumor immunity.
Mengshi Sun, Suhua Guan, Chenchen Yang…·Ling Chen
This study develops an oncolytic adenovirus that activates a prodrug to enhance tumor killing and antitumor immunity through direct oncolysis, bystander effects, and systemic immune responses.
DOI 10.64898/2026.05.26.727470