Author

Fraser Soares

University Health NetworkORCID 0000-0002-3977-7939Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Benjamin Haibe‐KainsiD· 2 shared Housheng Hansen HeiD· 2 shared Jie MingiD· 2 shared Moliang CheniD· 2 shared Mona TengiD· 2 shared Peter Hyunwuk HeriD· 2 shared Stanley LiuiD· 2 shared Tiantian LiiD· 2 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Benjamin Haibe‐KainsORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Sequence based prediction of cell type specific microRNA binding and mRNA degradation for therapeutic discovery

Bhargav Kanuparthi, Sara E. Pour, Scott D. Findlay, Omar Wagih, Jahir M. Gutierrez, Rory Gao, Jeff A. Wintersinger, Jiun-Nong Lin, Martino Gabra, Emma Bohn, Tammy Lau, Chris Cole, Andrew Jung, Albi Celaj, Fraser Soares, , Brendan J. Frey

This paper introduces REPRESS, a deep learning model that predicts cell-type-specific microRNA binding and mRNA degradation from RNA sequences, outperforming existing methods in multiple tasks.

bioRxiv · May 15, 2025 · PreprintGenomics

Functional landscape of circular RNAs in human cancer cells

Peter Hyunwuk Her, Tiantian Li, Ziwei Huang, Xin Xu, Weining Yang, Moliang Chen, Mona Teng, Sujun Chen, Yong Zeng, Stanley Liu, Benjamin Haibe‐Kains, Fraser Soares, Jie Ming, Housheng Hansen He

The paper identifies essential circRNAs in human cancer cells and introduces FunCirc, a database of functional circRNAs across cancer cell lines and tissues.

bioRxiv · Mar 24, 2025 · PreprintCancer Biology

Circular RNA profiling and functional screening in breast cancer identify circNSD1 as a suppressor of tumor autophagy

Wenhui Li, Wen Chun Yang, Peter Hyunwuk Her, Ting-Lin Yang, Tiantian Li, Ziwei Huang, Xin Xu, Mona Teng, Moliang Chen, Fraser Soares, Stanley Liu, Benjamin Haibe‐Kains, Housheng Hansen He, Jie Ming

The paper identifies circNSD1 as a tumor suppressor in breast cancer that inhibits autophagy and oxidative stress tolerance.

bioRxiv · Mar 24, 2025 · PreprintCancer Biology