Author

Laura Mainz

University of WürzburgORCID 0000-0002-3986-7547Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Almut SchulzeiD· 1 shared Andreas RosenwaldiD· 1 shared Apoorva BaluapuriiD· 1 shared Christina Schuelein‐Voelk· 1 shared Elena HartmanniD· 1 shared Elmar WolfiD· 1 shared Jennifer P. MortoniD· 1 shared Lisa SchlickeriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Almut SchulzeORCID

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1 paper

Recent·Most cited

Pharmacological arginine deprivation renders pancreatic cancer cells susceptible to senolysis and inhibition of the integrated stress response

Laura Mainz, Mohamed A.F.E. Sarhan, Lisa Schlicker, Stefanie Kirner, Jennifer P. Morton, Elena Hartmann, Andreas Rosenwald, Ursula Eilers, Christina Schuelein‐Voelk, Werner Schmitz, Apoorva Baluapuri, Martin Eilers, Elmar Wolf, Markus E. Diefenbacher, Almut Schulze, Mathias Tillmann Rosenfeldt

This study shows that arginine depletion induces senescence and stress response in pancreatic cancer cells, making them susceptible to senolysis and stress response inhibition.

bioRxiv · Aug 4, 2026 · PreprintCancer Biology