Author

Ying‐Xian Pan

Rutgers New Jersey Medical SchoolORCID 0000-0002-4006-8304Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Anjali M. RajadhyakshaiD· 2 shared Arlene Martínez-RiveraiD· 2 shared Ayma F. MalikiD· 1 shared Bing Wang· 1 shared Careen FoordiD· 1 shared Carlos M. CastorenaiD· 1 shared Conor M. ListoniD· 1 shared Diego Scala-CháveziD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

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10 top collaborators · 30 mutual co-author links

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2 shared papersNeuroscience

Anjali M. RajadhyakshaORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintAug 12, 2026

Reversible m6Am methylation of snRNA by FTO controls morphine reward and tolerance without altering analgesia

Shan Liu, Ayma F. Malik, Raymond Chien…·Ying‐Xian Pan

This study shows that FTO regulates morphine reward and tolerance through m6Am methylation of snRNA, without affecting analgesia.

DOI 10.64898/2026.08.06.743062

mousebulk RNA-seq

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NeuroscienceScience AdvancesPeer-reviewedNov 29, 2024

Elevating levels of the endocannabinoid 2-arachidonoylglycerol blunts opioid reward but not analgesia

Arlene Martínez-Rivera, Robert N. Fetcho, Lizzie Birmingham…·Francis S. Lee

This study shows that increasing 2-AG levels reduces opioid reward but not analgesia in mice, suggesting a potential therapeutic strategy for pain treatment.

17 citationstop 4%

mouseexperimental assay

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