Conor M. Liston

The paper investigates how serotonergic and GABAergic neurons in the dorsal raphe nucleus contribute to effort-based decision-making by analyzing their activity during a task.

This study identifies the role of dorsal raphe nucleus neurons in stress-induced shifts from goal-directed to habit-driven behavior using mouse models and molecular profiling.

The paper identifies stress-induced changes in frontocortical cellular communication and neuropeptide signaling associated with motivational impairment in mice.

The paper introduces NSI, an objective measure to assess data quality for precision functional MRI, aligning with expert evaluations and enabling principled decisions on data sufficiency.

The paper identifies parallel processing chains in association cortex using multiple functional mapping modalities, showing they are experience-driven and organized across different cytoarchitectures.

This study finds that cocaine use disorder is linked to reduced brain state transition energy in specific networks, particularly those involved in excitatory and higher-order functions.

This study shows that nitrous oxide increases cortical activity, alters wake-sleep oscillations, and produces antidepressant-like effects in mice, similar to ketamine.

This study shows that increasing 2-AG levels reduces opioid reward but not analgesia in mice, suggesting a potential therapeutic strategy for pain treatment.

This paper develops magnetogenetic tools to bidirectionally regulate specific neuronal circuits in vivo using magnetic fields and shows their efficacy in motor control and Parkinson's models.

The paper develops and evaluates dimensional and categorical approaches to identify depression subtypes using brain-behavior dimensions and clustering in a large single-site sample of MDD patients and controls.

The paper uses photopharmacology to show that mGluR2 in specific brain projections regulates distinct anxiety-related behaviors.

This study identifies a drug cocktail that accelerates maturation of hPSC-derived neurons and other cell types through pharmacological intervention.

This study shows that adolescent medial prefrontal cortex (mPFC) neurons are hyper-responsive to reward cues and encode them differently than adult mPFC neurons, affecting reward motivation.

The paper identifies a two-fold expansion of the frontostriatal salience network in individuals with depression using longitudinal neuroimaging data and shows its stability over time and predictive value for future symptoms.

The paper reveals that motor cortex contains inter-effector regions connected to the Cingulo-opercular network, alternating with effector-specific areas, suggesting a dual system for motor control and whole-body coordination.

The paper examines the relationship between white matter hyperintensity burden, resting state functional connectivity, and cognitive functions in older adults, finding associations with memory retrieval but not other cognitive tasks.

This study shows that astrocytes from ASD patients induce repetitive behavior and impair memory when transplanted into healthy mice, suggesting a primary role for astrocytes in ASD.

This study identifies deep prefrontal projection neurons as critical for cognitive flexibility by monitoring behavioral feedback through persistent activity.

The paper identifies epigenetically bistable regions in neuronal genes that influence neuronal eligibility for coding ensembles in the hippocampus, showing their role in spatial memory and excitability.

This study identifies stress-responsive neurons in the lateral septum that reduce food intake and body weight through hypothalamic pathways.

The paper re-evaluates the stability of canonical correlations between functional connectivity and depressive symptoms using optimized statistical methods and demonstrates how optogenetic fMRI can test subtype-specific circuit mechanisms in depression.

The paper introduces SWIFT, a computational imaging method for capturing coordinated neuronal activity across large tissue volumes in mammals at high speed and resolution.