Author

Jiajun Cai

Fudan UniversityORCID 0000-0002-4024-8380Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Jia FaniD· 1 shared Jia Yu· 1 shared Jianhang Huang· 1 shared Jianing ZhaoiD· 1 shared Jie WangiD· 1 shared Qin Feng· 1 shared Ruijie GongiD· 1 shared Siyuan XuiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Jia FanORCID

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1 paper

Recent·Most cited

BRD8 Disruption Unlocks Retrotransposon-Driven Tumor-Intrinsic Immunogenicity via Redistribution of Histone Acetylation in Liver Cancer

Ruijie Gong, Yijie Shen, Jianhang Huang, Jie Wang, Siyuan Xu, Songchen Liu, Qin Feng, Jia Yu, Jianing Zhao, Jia Fan, Jiajun Cai, Xianjiang Lan

This study identifies BRD8 as an epigenetic suppressor of tumor-intrinsic immunity in liver cancer, showing its depletion enhances immunogenicity and sensitizes tumors to immunotherapy.

bioRxiv · Jan 23, 2026 · PreprintCancer Biology