Fred William Turek

Disrupted sleep-wake regulation in the MCI-Park mouse model of Parkinson's Disease

The paper studies sleep-wake abnormalities in a new PD mouse model and finds they mirror human PD symptoms, suggesting potential for understanding and treating sleep disruptions in PD.

Immunization with Mycobacterium vaccae NCTC 11659 prevents the development of PTSD- like sleep and behavioral phenotypes after sleep disruption and acute stress in mice

Altered Affective Behaviors in Casein Kinase 1 Epsilon Mutant Mice

This study examines affective behaviors in mice with mutations in the CSNK1E gene, finding altered anxiety, fear, and depressive-like behaviors that vary by mutation type, sex, and light cycle.

Distinct ipRGC subpopulations mediate light’s acute and circadian effects on body temperature and sleep

The paper shows that a specific subpopulation of ipRGCs projecting to the SCN mediates light's acute effects on body temperature and sleep, while other ipRGCs are involved in circadian regulation.

Intercellular signaling network underlies biological time across multiple temporal scales

The paper identifies a multiscale temporal regulatory network involving genes that regulate circadian, cell cycle, and aging processes, enriched for signal transduction, metabolism, and stress response genes.