Alan C. Rupp

This study identifies a single dorsal vagal complex circuit that mediates both aversive and anorectic responses to GLP1R agonists, showing that APGlp1r neurons are responsible for both effects.

The paper identifies a distinct RSG neuron subtype, LR neurons, that lacks persistent firing in response to cholinergic agonists, enabling consistent angular head velocity computation across brain states.

This study shows that neuronal SEL1L-HRD1 ERAD is critical for one-carbon metabolism, motor function, and survival, with loss leading to severe neurological defects.

The paper identifies a conserved population of GABAergic Glp1r-expressing LepRb neurons that mediate leptin's suppression of food intake and prevention of obesity.

The paper identifies conserved VMH neuron populations across species using TRAP-seq and snRNA-seq data, defining six major neuron classes with distinct anatomical and genetic features.

This study identifies GFRAL-expressing neurons in the hindbrain that suppress food intake through aversive pathways by responding to non-meal-related signals.

The paper shows that a specific subpopulation of ipRGCs projecting to the SCN mediates light's acute effects on body temperature and sleep, while other ipRGCs are involved in circadian regulation.