Author

Michael H. Nichols

Emory UniversityORCID 0000-0002-4036-1586Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Organism:Drosophila· 1 Research Focus:fine-mapping· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1

Frequent Co-Authors

Victor G. CorcesiD· 2 shared A. Gesine CaueriD· 1 shared Achyuth KalluchiiD· 1 shared Ailun WangiD· 1 shared Akshay KrishnaiD· 1 shared Arina D. OmeriD· 1 shared Aviva Presser AideniD· 1 shared Devika Udupa· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Victor G. CorcesORCID

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2 papers

Recent·Most cited

Fine-mapping of nuclear compartments using ultra-deep Hi-C shows that active promoter and enhancer elements localize in the active A compartment even when adjacent sequences do not

Hannah L. Harris, Huiya Gu, Moshe Olshansky, Ailun Wang, Irene Farabella, Yossi Eliaz, Achyuth Kalluchi, Akshay Krishna, Mozes Jacobs, A. Gesine Cauer, Melanie Pham, Suhas S.P. Rao, Olga Dudchenko, Arina D. Omer, Kiana Mohajeri, , M. Jordan Rowley

The paper uses ultra-deep Hi-C and a new computational method to fine-map nuclear compartments, revealing that active promoters and enhancers localize in the A compartment even when adjacent sequences are inactive.

Nature Communications · Jun 6, 2023Peer-reviewedGenomics

Principles of 3D Compartmentalization of the Human Genome

Michael H. Nichols, Victor G. Corces

The paper identifies different types of compartmental domains in human chromosomes and presents a computational model to predict their organization based on chromatin features.

Cell Reports · Jun 1, 2021Peer-reviewedBioinformatics