Meclizine and metabotropic glutamate receptor agonists attenuate severe pain and primary sensory neuron Ca2+ activity in chemotherapy-induced peripheral neuropathy
John L. Shannonhouse, Matteo Bernabucci, Rubén Sánchez Gómez…·Yu Shin Kim
This study tests mGluR agonists and meclizine as treatments for CIPN, finding they reduce pain and DRG neuron Ca2+ activity in a mouse model.