Author

Hassan Ashktorab

Howard UniversityORCID 0000-0002-4048-4666Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Approach:statistical model· 2

Frequent Co-Authors

Duane T. Smoot· 2 shared Akira IshikawaiD· 1 shared Alfred Sze‐Lok ChengiD· 1 shared Anand Devaprasath D. JeyasekharaniD· 1 shared Andrada Birladeanu· 1 shared Angie Lay Keng TaniD· 1 shared Aya Kido· 1 shared Chang XuiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersPathology

Duane T. Smoot

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3 papers

Recent·Most cited

Single-cell Pharmacogenomic Landscapes of Epigenetic Drug Resistance Revealed by Gastric Cancer Perturb-seq

Chang Xu, Haoran Ma, Taotao Sheng, Ming Hui Lee, Siti Aishah Binte Abdul Ghani, Laura Perlaza-Jiménez, Kie Kyon Huang, Shen Kiat Lim, Supriya Srivastava, Xuewen Ong, Su Ting Tay, Shamaine Wei Ting Ho, Zhi Xuan Ong, Angie Lay Keng Tan, Feng Zhu, , Patrick B. O. Tan

This study uses Perturb-seq to analyze pharmacogenomic interactions in gastric cancer, revealing gene-drug relationships and resistance mechanisms.

bioRxiv · Apr 16, 2025 · PreprintCancer Biology

Discovering cancer stem-like cells using Spatial transcriptomic analysis: Nuclear factor I X as a novel therapeutic target for gastric cancer

Akira Ishikawa, Takafumi Fukui, Aya Kido, Narutaka Katsuya, Kazuya Kuraoka, Naohiro Uraoka, Takahisa Suzuki, Shiro Oka, Takahiro Kotachi, Hassan Ashktorab, Duane T. Smoot, Wataru Yasui

This study identifies NFIX as a critical regulator of cancer stemness in gastric cancer using spatial transcriptomic analysis and shows its correlation with poor prognosis.

Cancer Science · Jul 17, 2024Peer-reviewedPathology

Communication between the nucleus and the mitochondria via NDUFS4 alternative splicing in gastric cancer cells

Vasiliki Papadaki, Zoi Erpapazoglou, Maria Kokkori, Malgorzata Ewa Rogalska, Myrto Potiri, Andrada Birladeanu, Eleni N. Tsakiri, Hassan Ashktorab, Duane T. Smoot, Katerina Papanikolopoulou, Martina K. Samiotaki, Panagiota Kafasla

The paper shows IQGAP1 regulates NDUFS4 alternative splicing, affecting mitochondrial complex I function in gastric cancer cells.

NAR Cancer · Jun 9, 2023Peer-reviewedMolecular Biology