Panagiota Kafasla

RpS12-mediated induction of the Xrp1short isoform links ribosomal protein mutations to cell competition

The paper shows that RpS12 induces the Xrp1short isoform in Rp+/- cells, which is necessary and sufficient for their elimination, challenging existing models of ribosomal protein-linked fitness surveillance.

A neural alternative splicing program controls cellular function and growth in Pancreatic Neuroendocrine tumours

This study identifies an alternative splicing program regulated by SRRM3 that affects secretory function and neuronal characteristics in PanNETs, offering therapeutic targets.

Communication between the nucleus and the mitochondria via NDUFS4 alternative splicing in gastric cancer cells

The paper shows IQGAP1 regulates NDUFS4 alternative splicing, affecting mitochondrial complex I function in gastric cancer cells.

The scaffold protein IQGAP1 links heat-induced stress signals to alternative splicing regulation in gastric cancer cells

This study identifies IQGAP1 as a scaffold protein linking heat-induced stress signals to alternative splicing regulation in gastric cancer cells, showing its role in controlling hnRNPM sumoylation and AS of a cell cycle-related RNA regulon.