Sandra Schick

The paper uses microscopy and field theory to show transcriptional condensates exhibit size control through non-equilibrium dynamics.

The paper quantifies transcriptional condensate states using chemical perturbations and finds BRD4-only condensates that are acetylation-dependent and distinct from canonical transcriptionally engaged condensates.

This study systematically profiles drug responses in BAF complex perturbations, revealing subtype-specific vulnerabilities and resistance patterns to genotoxic and cytotoxic compounds.