Author

Christian Schäfer

Institute of Molecular BiologyORCID 0000-0002-9840-2870Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Eric SchumberaiD· 2 shared Katja LuckiD· 2 shared Mareen WelzeliD· 2 shared Caroline BarryiD· 1 shared Chop Yan LeeiD· 1 shared Christina NtasiouiD· 1 shared Claudia Isabelle Keller ValsecchiiD· 1 shared Dalmira HubrichiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMolecular Biology

Eric SchumberaORCID

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2 papers

Recent·Most cited

Systematic drug profiling across BAF complex perturbations reveals distinct dependencies

Katharina Spang, Caroline Barry, Christina Ntasiou, Eleni Aretaki, Mara Wolf, Eric Schumbera, Fridolin Kielisch, Lena Bonn, Mareen Welzel, Frank Rühle, Christian Schäfer, Katja Luck, Sandra Schick

This study systematically profiles drug responses in BAF complex perturbations, revealing subtype-specific vulnerabilities and resistance patterns to genotoxic and cytotoxic compounds.

bioRxiv · Mar 13, 2026 · PreprintMolecular Biology

Systematic discovery of protein interaction interfaces using AlphaFold and experimental validation

Chop Yan Lee, Dalmira Hubrich, Julia K. Varga, Christian Schäfer, Mareen Welzel, Eric Schumbera, Milena Djokic, Joelle Morgan Strom, Jonas Schönfeld, Johanna Lena Geist, Feyza Polat Haas, Toby J. Gibson, Claudia Isabelle Keller Valsecchi, Manjeet Kumar, Ora Schueler‐Furman, Katja Luck

The paper evaluates AlphaFold-Multimer for predicting protein interaction interfaces using short linear motifs and validates some predictions experimentally.

Molecular Systems Biology · Jan 15, 2024Peer-reviewedSystems Biology