Author

Joshua J. Lingo

University of Colorado AnschutzORCID 0000-0002-4089-9052Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Galen T SquiersiD· 2 shared Jason C. KleiniD· 2 shared Maggie M. BalasiD· 2 shared Alexander W. BoydeniD· 1 shared Ali JabbariiD· 1 shared Arjun M. BashyamiD· 1 shared Benjamin A. NanesiD· 1 shared Benjamin W. DarbroiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersGenomics

Galen T SquiersORCID

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3 papers

Recent·Most cited

Perturb-seq resolves physiologic programs and bidirectional regulation of non-canonical NF-κB signaling in epidermal organoids

Galen T Squiers, Benjamin A. Nanes, Maggie M. Balas, Joshua J. Lingo, L H Wang, Huan Zhao, Sabahat Munawar, Mpathi Nzima, Gary C. Hon, Jason C. Klein

The paper uses Perturb-seq in epidermal organoids to study non-canonical NF-κB signaling's role in keratinocyte differentiation.

bioRxiv · Jul 23, 2026 · PreprintGenomics

Intratumoral plasma cells are required for activation of CD8+ T cells and success of immune checkpoint blockade therapy in de novo MPNSTs

Joshua J. Lingo, Ryan J. Reis, Chantal Allamargot, Juan A. Raygoza Garay, Courtney A. Kaemmer, Elizabeth C. Elias, Ellen M. Voigt, Ali Jabbari, Connor R. Wilhelm, Alexander W. Boyden, Nitin J. Karandikar, Patrick John Breheny, David Kyle Meyerholz, Rebecca D. Dodd, Jon C. D. Houtman, , Dawn E. Quelle

This study shows that intratumoral plasma cells are essential for CD8+ T cell activation and response to immune checkpoint blockade therapy in MPNSTs.

bioRxiv · Feb 20, 2026 · PreprintCancer Biology

Proteomics and single-cell transcriptomics identify LRP1 as a diagnostic biomarker for atypical fibroxanthoma and pleomorphic dermal sarcoma.

Joshua J. Lingo, Maggie M. Balas, Arjun M. Bashyam, Gregory A. Hosler, Galen T Squiers, Jason C. Klein

The paper identifies LRP1 as a more accurate biomarker for diagnosing atypical fibroxanthoma and pleomorphic dermal sarcoma compared to existing markers.

bioRxiv · Feb 9, 2026 · PreprintCancer Biology