Author

Kristijonas Žemaitis

Lund UniversityORCID 0000-0002-4098-0184Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Abhishek NiroulaiD· 1 shared Agatheeswaran SubramaniamiD· 1 shared Aitzkoa Lopez de Lapuente PortillaiD· 1 shared Anne de Snaijer· 1 shared Antton Lamarca ArrizabalagaiD· 1 shared Björn NilssoniD· 1 shared Caterina CafaroiD· 1 shared David Linfeldt· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenomics

Abhishek NiroulaORCID

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2 papers

Recent·Most cited

Cancer-associated KBTBD4 mutations induce differentiation defects and confer a unique therapeutic vulnerability

Rohit Sivaprasad, Kristijonas Žemaitis, David Linfeldt, Sudip Ghosh, Anne de Snaijer, Mattias Magnusson, Fredrik Ek, Jenny Hansson, Agatheeswaran Subramaniam

This study models KBTBD4 mutations in hematopoietic stem cells, identifies HDAC inhibitors as therapeutic agents, and reveals their mechanism of action.

Cancer Gene Therapy · Aug 10, 2026Peer-reviewedCancer Biology

Genome-wide association study on 13,167 individuals identifies regulators of hematopoietic stem and progenitor cell levels in human blood

Aitzkoa Lopez de Lapuente Portilla, Ludvig Ekdahl, Caterina Cafaro, Zain Ali, Natsumi Miharada, Gudmar Thorleifsson, Kristijonas Žemaitis, Antton Lamarca Arrizabalaga, Malte Thodberg, Maroulio Pertesi, Parashar Dhapola, Erik L. Bao, Abhishek Niroula, Divya Bali, Gudmundur Norddahl, , Björn Nilsson

A genome-wide association study identifies DNA variants influencing HSPC levels in human blood, with PPM1H as a novel regulator affecting stem cell subpopulations.

Blood · Jan 10, 2022Peer-reviewedGenomics