Author

Yara Rodríguez

Broad InstituteORCID 0000-0002-4121-5740Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Allen Thayakumar BasanthakumariD· 1 shared Ashleigh MeyeriD· 1 shared Audrey TailloniD· 1 shared Björn HäupliD· 1 shared Constanze SchneideriD· 1 shared David E. RootiD· 1 shared Dipanjan ChowdhuryiD· 1 shared Fabio Boniolo· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Allen Thayakumar BasanthakumarORCID

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1 paper

Recent·Most cited

Chromatin Perturbation Promotes Susceptibility to Hypomethylating Agents

Constanze Schneider, Gabriela Alexe, Lucy A. Merickel, Ashleigh Meyer, Michelle L. Swift, Rodolfo Bortolozo Serafim, Allen Thayakumar Basanthakumar, Audrey Taillon, Silvi Salhotra, Fabio Boniolo, Sander Lambo, Yara Rodríguez, Björn Häupl, Rani E. George, David E. Root, , Kimberly Stegmaier

The paper identifies USP48 as a regulator of chromatin stability and DNA damage response to hypomethylating agents, showing its loss increases susceptibility to these drugs in AML.

bioRxiv · Jul 28, 2025 · PreprintCancer Biology