Author

Eszter Zavodszky

MRC Laboratory of Molecular BiologyORCID 0000-0002-4123-8758Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Paul V. MurphyiD· 2 shared Ramanujan S. HegdeiD· 2 shared Tim ClauseniD· 2 shared Alexander SchleifferiD· 1 shared Alexandra ShulkinaiD· 1 shared Anton MeinhartiD· 1 shared Daniel B. GrabarczykiD· 1 shared Gijs A. VersteegiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

Paul V. MurphyORCID

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2 papers

Recent·Most cited

BiochemistrySciencePeer-reviewedAug 28, 2025

Architecture of the UBR4 complex, a giant E4 ligase central to eukaryotic protein quality control

Daniel B. Grabarczyk, Julian F. Ehrmann, Paul V. Murphy…·Tim Clausen

The paper presents the cryo-EM structure of the UBR4 complex, revealing its architecture and mechanism for substrate binding and ubiquitin chain extension in protein quality control.

20 citationstop 3%

experimental assayprotein folding & dynamics

𝕏 PostBluesky

Cell BiologyMolecular CellPeer-reviewedJan 28, 2025

Convergence of orphan quality control pathways at a ubiquitin chain-elongating ligase

Sara Carrillo Roas, Yuichi Yagita, Paul V. Murphy…·Ramanujan S. Hegde

The paper identifies the UBR4-KCMF1 ubiquitin ligase complex as a convergence point for quality control pathways that degrade orphan subunits, highlighting its role in protein homeostasis and cancer vulnerability.

20 citationstop 3%

experimental assaychromatin & epigenetic regulation

𝕏 PostBluesky