S. Bhatt

This paper introduces a bioengineered stem cell organoid system to model human neural crest development, showing it recapitulates key developmental dynamics and can be used for cross-species validation.

This study shows that inhibiting LSD1, a histone demethylase, restores learning and memory in aged mice by reversing age-related defects in H3K4me3 dynamics and synaptic plasticity.

This paper uses mass spectrometry to identify age- and activity-dependent changes in histone post-translational modifications in mouse hippocampi, proposing a framework for integrating these findings into ageing research.

This study shows that KDM5B deficiency in mice leads to autism-like behaviors and increased brain size, which can be mitigated by NMDAR antagonists.