Laurent Perrin

The paper identifies genes and secreted proteins modulated by High Fat and High Sugar diets in Drosophila hearts, revealing adaptive responses to nutritional stress.

The paper uses Drosophila to test if genes near BrS risk loci affect cardiac function, identifying potential candidates for further study.

The paper identifies genetic factors influencing cardiac aging in Drosophila by analyzing natural variation and highlights Pdp1's role in cardiac senescence through mitochondrial regulation.

The paper identifies genetic networks and regulatory elements associated with cardiac performance variation in Drosophila and finds conserved genetic architecture between flies and humans.

The paper introduces epiMEIF, a method for detecting high-order epistatic interactions in GWAS data, showing its effectiveness through simulations and an application to Drosophila cardiac traits.