Author

Laurence Röder

InsermORCID 0000-0002-6193-4531Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:Drosophila· 4 Approach:statistical model· 4 Research Focus:gene regulatory network inference· 3 Research Focus:differential expression· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Laurent PerriniD· 4 shared Sallouha KrifaiD· 3 shared Saswati SahaiD· 3 shared Christine BruniD· 2 shared Laurent Kremmer· 2 shared Lionel SpinelliiD· 2 shared Magali TorresiD· 2 shared Nathalie ArquieriD· 2 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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4 shared papersGenetics

Laurent PerrinORCID

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4 papers

Recent·Most cited

PhysiologyPLoS GeneticsPeer-reviewedJun 11, 2026

Metabolism fine tuning and cardiokines secretion represent adaptative responses of the heart to High Fat and High Sugar Diets in flies

Lucie Khamvongsa-Charbonnier, Laurent Kremmer, Magali Torres…·Nathalie Arquier

The paper identifies genes and secreted proteins modulated by High Fat and High Sugar diets in Drosophila hearts, revealing adaptive responses to nutritional stress.

1 citation

Drosophilabulk RNA-seq

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GeneticsbioRxivPreprintSep 30, 2024

Natural variations of cardiac performance in Drosophila identify a central function for Pdp1/dHLF in cardiac aging

Katell Audouin, Saswati Saha, Laurence Röder…·Laurent Perrin

The paper identifies genetic factors influencing cardiac aging in Drosophila by analyzing natural variation and highlights Pdp1's role in cardiac senescence through mitochondrial regulation.

1 citation

Drosophilastatistical model

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GeneticseLifePeer-reviewedOct 26, 2022

Genetic architecture of natural variation of cardiac performance in flies: from flies to Humans

Saswati Saha, Lionel Spinelli, Jaime Abraham Castro Mondragón…·Laurent Perrin

The paper identifies genetic networks and regulatory elements associated with cardiac performance variation in Drosophila and finds conserved genetic architecture between flies and humans.

12 citations

Drosophilastatistical model

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GeneticsNucleic Acids ResearchPeer-reviewedSep 15, 2022

Epi-MEIF, a flexible and efficient method for detection of high order epistatic interactions from complex phenotypic traits

Saswati Saha, Laurent Perrin, Laurence Röder…·Lionel Spinelli

The paper introduces epiMEIF, a method for detecting high-order epistatic interactions in GWAS data, showing its effectiveness through simulations and an application to Drosophila cardiac traits.

14 citations

DrosophilaGWAS summary statistics

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