Author

R. Anahí Higuera-Rodríguez

Dynamic Biosensors (Germany)ORCID 0000-0002-4170-8799Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Approach:deep learning· 1 Organism:E. coli· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:protein design· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1

Frequent Co-Authors

Anna Pérez‐RàfolsiD· 2 shared Guillermo Pérez-RoperoiD· 2 shared Jos BuijsiD· 2 shared Tommaso MartelliiD· 2 shared W. KaiseriD· 2 shared Wim VrankeniD· 2 shared Alejandro Requena-MenéndeziD· 1 shared Alessandro ProvenzaniiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersBiophysics

Anna Pérez‐RàfolsORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Deciphering the RNA recognition by Musashi-1 to design protein and RNA mutants for in vitro and in vivo applications

Anna Pérez‐Ràfols, Guillermo Pérez-Ropero, Linda Cerofolini, Luca Sperotto, Joel Roca‐Martínez, R. Anahí Higuera-Rodríguez, Pasquale Russomanno, W. Kaiser, Wim Vranken, U. Helena Danielson, Alessandro Provenzani, Tommaso Martelli, Michael Sattler, Jos Buijs, Marco Fragai

The paper uses structural biology and computational methods to design MSI-1 mutants that alter RNA binding selectivity, validated by NMR and SPR experiments.

Nucleic Acids Research · Jul 24, 2025Peer-reviewedBiophysics

Repurposing the mammalian RNA-binding protein Musashi-1 as an allosteric translation repressor in bacteria

Roswitha Dolcemascolo, María Heras‐Hernández, Lucas Goiriz, Roser Montagud‐Martínez, Alejandro Requena-Menéndez, Raúl Ruiz, Anna Pérez‐Ràfols, R. Anahí Higuera-Rodríguez, Guillermo Pérez-Ropero, Wim Vranken, Tommaso Martelli, W. Kaiser, Jos Buijs, Guillermo Rodrigo

This paper engineers a bacterial gene regulation system using the mammalian RNA-binding protein Musashi-1 to repress translation through an allosteric mechanism.

eLife · Oct 12, 2023Peer-reviewedSynthetic Biology