Author

Linda Cerofolini

Consorzio Interuniversitario Risonanze Magnetiche di Metallo ProteineORCID 0000-0002-0795-9594Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:bacteria (other)· 1 Approach:deep learning· 1 Research Focus:protein design· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1

Frequent Co-Authors

Marco FragaiiD· 3 shared Alessandro ProvenzaniiD· 1 shared Anna KabanovaiD· 1 shared Anna Pérez‐RàfolsiD· 1 shared Annabelle VarrotiD· 1 shared Annalisa CiabattiniiD· 1 shared Anne ImbertyiD· 1 shared Cesira GiordanoiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersBiochemistry

Marco FragaiORCID

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3 papers

Recent·Most cited

Structural Basis for Human Milk Oligosaccharides Recognition by Evolutionarily Dominant Norovirus Genogroup II Genotypes

Luca Pisapia, Henry N. Flatau, Siyu Lin, Rebecca Calamandrei, Linda Cerofolini, Juan C. Muñoz-García, Anne Imberty, Marco Fragai, Jesus Angulo, Annabelle Varrot

This study investigates how different norovirus genotypes recognize human milk oligosaccharides using structural and biochemical methods, revealing genotype-specific binding mechanisms.

bioRxiv · Nov 4, 2026 · PreprintBiochemistry

Anti-capsule human monoclonal antibodies protect against hypervirulent and pandrug-resistant Klebsiella pneumoniae

Emanuele Roscioli, Vittoria Zucconi Galli Fonseca, Soraya Soledad Bosch, Ida Paciello, Giuseppe Maccari, Giulia Cardinali, Giampiero Batani, Samuele Stazzoni, Giusy Tiseo, Cesira Giordano, Yuwei Shen, Laura Capoccia, Dario Cardamone, Matteo Ridelfi, Marco Troisi, , Rino Rappuoli

This study isolates human monoclonal antibodies against hypervirulent, pandrug-resistant Klebsiella pneumoniae and identifies capsule-specific antibodies as protective against bloodstream infection.

Nature · Oct 1, 2025Peer-reviewedMicrobiology

Deciphering the RNA recognition by Musashi-1 to design protein and RNA mutants for in vitro and in vivo applications

Anna Pérez‐Ràfols, Guillermo Pérez-Ropero, Linda Cerofolini, Luca Sperotto, Joel Roca‐Martínez, R. Anahí Higuera-Rodríguez, Pasquale Russomanno, W. Kaiser, Wim Vranken, U. Helena Danielson, Alessandro Provenzani, Tommaso Martelli, Michael Sattler, Jos Buijs, Marco Fragai

The paper uses structural biology and computational methods to design MSI-1 mutants that alter RNA binding selectivity, validated by NMR and SPR experiments.

Nucleic Acids Research · Jul 24, 2025Peer-reviewedBiophysics