Heiko Locher

This study develops patient-derived inner ear organoids to evaluate antisense oligonucleotide therapies for hereditary hearing loss, showing effective ASO uptake and splice correction in disease models.

This study compares single-cell transcriptomic profiles of human inner ear organoids with fetal and adult inner ear tissues to assess their ability to model inner ear disorders.

This study compares human iPSC-derived inner ear organoids with early embryonic inner ear tissue, showing they recapitulate key developmental stages and marker expression.