Maria Lindskog

GABA-induced Ca2+ signaling in the primary cilium of neurons

This study shows that GABA receptor subtype 1 localizes to primary cilia of neurons and initiates ciliary Ca2+ signaling, distinct from its inhibitory role in other neuronal domains.

Early astrocytic dysfunction is associated to mistuned synapses as well as anxiety and depressive-like behavior in the AppNL-F mouse model of Alzheimers disease

The paper investigates early synaptic dysfunction and emotional behavior in AppNL-F mice, finding reactive astrocytes contribute to synaptic mistuning before Aβ plaques and are linked to depressive-like behavior.

Impaired glutamate reuptake induces synaptic mistuning in rat hippocampal slices, that can be counteracted by ketamine

The paper shows that impaired glutamate reuptake in rat hippocampal slices leads to synaptic mistuning, which ketamine can counteract by restoring synaptic tuning.