Author

Robert Ciarán Prior

University of BonnORCID 0000-0002-4184-0693Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

Ludo Van Den BoschiD· 2 shared Philip Van DammeiD· 2 shared Adekunle T. BademosiiD· 1 shared Adrià SicartiD· 1 shared Alessio SilvaiD· 1 shared Arun Kumar TharkeshwariD· 1 shared Bastijn KoopmansiD· 1 shared Carlotta BorgarelliiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

Ludo Van Den BoschORCID

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2 papers

Recent·Most cited

MeFluHyA: a novel fluorescent screening tool for high-throughput identification of HDAC6-selective inhibitors

Yvonne Eileen Klingl, Jozefien Goethals, Adrià Sicart, Carlotta Borgarelli, Joris Van Lindt, Robert Ciarán Prior, Ermal Ismalaj, Wim M. De Borggraeve, Philip Van Damme, Jacob M. Hooker, Michele Curcio, Steven H. L. Verhelst, Matthias Schönberger, Ludo Van Den Bosch

The paper introduces MeFluHyA, a fluorescent probe for identifying HDAC6-selective inhibitors through cell imaging and competitive binding assays.

bioRxiv · Jul 27, 2026 · PreprintBiochemistry

Defective Schwann cell lipid metabolism alters plasma membrane dynamics in Charcot-Marie-Tooth disease 1A

Robert Ciarán Prior, Alessio Silva, Tim Vangansewinkel, Jakub Idkowiak, Arun Kumar Tharkeshwar, Tom P. Hellings, Iliana Michailidou, Jeroen P. Vreijling, Maarten Loos, Bastijn Koopmans, Nina Vlek, Nina Straat, Cedrick Agaser, Thomas B. Kuipers, Christine Michiels, , Ludo Van Den Bosch

This study identifies defective lipid metabolism in Schwann cells as a cause of CMT1A, showing altered lipid composition and membrane dynamics in mouse models and human iPSC-derived cells.

bioRxiv · Apr 2, 2023 · PreprintNeuroscience