Author

Nina Straat

Amsterdam UMC Location Vrije Universiteit Amsterdam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Adekunle T. BademosiiD· 1 shared Adri A.M. Thomas· 1 shared Alessio SilvaiD· 1 shared Arun Kumar TharkeshwariD· 1 shared Bastijn KoopmansiD· 1 shared Cedrick Agaser· 1 shared Christine MichielsiD· 1 shared Daniel Voltolini‐González· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Adekunle T. BademosiORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Defective Schwann cell lipid metabolism alters plasma membrane dynamics in Charcot-Marie-Tooth disease 1A

Robert Ciarán Prior, Alessio Silva, Tim Vangansewinkel, Jakub Idkowiak, Arun Kumar Tharkeshwar, Tom P. Hellings, Iliana Michailidou, Jeroen P. Vreijling, Maarten Loos, Bastijn Koopmans, Nina Vlek, Nina Straat, Cedrick Agaser, Thomas B. Kuipers, Christine Michiels, , Ludo Van Den Bosch

This study identifies defective lipid metabolism in Schwann cells as a cause of CMT1A, showing altered lipid composition and membrane dynamics in mouse models and human iPSC-derived cells.

bioRxiv · Apr 2, 2023 · PreprintNeuroscience

Integrated Stress Response Deregulation underlies Vanishing White Matter and is a target for therapy

Truus E. M. Abbink, Lisanne E. Wisse, Ermelinda Jaku, Michiel J. Thiecke, Daniel Voltolini‐González, Hein Fritsen, Sander Bobeldijk, Timo J. ter Braak, Emiel Polder, Nienke L. Postma, Marianna Bugiani, Eduard A. Struijs, Mark H. G. Verheijen, Nina Straat, Sophie van der Sluis, , Marjo S. van der Knaap

ISRIB ameliorates ISR deregulation and clinical signs in VWM mice.

bioRxiv · Dec 4, 2018 · PreprintNeuroscience