Adekunle T. Bademosi

The paper shows that single-molecule bouncing at a presynaptic interface enables protein enrichment without slowing diffusion.

This study identifies Vaultrc5 as a noncoding RNA that regulates synaptic vault trafficking and RNA cargo dynamics, impacting learning and memory.

This study shows that transmitted alpha-synuclein extracellular vesicles reduce retrograde axonal transport in recipient neurons, with effects dependent on endogenous alpha-synuclein interaction.

The paper identifies synaptic dysfunction in cholinergic projection neurons as an early indicator of Parkinsonism across multiple fly models and links it to olfactory dysfunction and dopaminergic decline.

This study identifies persistent extra-motor behavioural deficits in rNLS8 TDP-43 mice, linked to synaptic gene expression and splicing changes that persist even after motor recovery.

The paper identifies a lncRNA, Gas5, involved in fear extinction by regulating RNA granule trafficking and clustering at synapses in mice.

This study identifies a transient protein folding response in early TDP-43 disease that reduces aggregation, with DNAJB5 as a protective factor, and shows proteomic similarities between mouse and human TDP-43 proteinopathies.

This study identifies defective lipid metabolism in Schwann cells as a cause of CMT1A, showing altered lipid composition and membrane dynamics in mouse models and human iPSC-derived cells.

This study shows isoflurane selectively impairs Syntaxin1A activity at cholinergic synapses in Drosophila excitatory neurons, but not in inhibitory neurons.

This study investigates how RNA-binding deficiency and post-translational modifications of TDP-43 lead to its sequestration and depletion, contributing to neurodegeneration in ALS and FTD.

The paper shows how EndophilinA couples calcium influx to synaptic autophagy and identifies a Parkinson-risk mutation that disrupts this process.