Michael T. Bailey

The Nox2 NADPH oxidase regulates neutrophilic inflammation in the oral cavity

This study shows that Nox2 oxidase regulates neutrophilic inflammation in the oral cavity through Nrf2-dependent mechanisms, independent of its antimicrobial role.

Social stress worsens colitis through beta-adrenergic-driven oxidative stress in intestinal mucosal compartments

This study shows social stress worsens colitis via beta-adrenergic and NADPH oxidase-driven oxidative stress, with beta-blockers and apocynin reducing inflammation.

Aging amplifies a gut microbiota immunogenic signature linked to heightened inflammation

This study shows that aging alters gut microbiota immunogenicity, increasing TLR4 activation and inflammation, and that these changes are linked to heightened host inflammation.