Steven W. Singer

CAZyme domain architectures suggest fine-scale functional differentiation among anaerobic fungi and bacteria during lignocellulose conversion to volatile fatty acids

Feedstock-Efficient Conversion through Hydrogen and Formate-Driven Metabolism in Escherichia coli

This paper engineers Escherichia coli to use hydrogen and formate as energy sources, improving mevalonate production by 57.6% through metabolic decoupling.

Functional plasticity of HCO3- uptake and CO2 fixation in Cupriavidus necator H16

This study investigates the functional plasticity of HCO3- uptake and CO2 fixation in C. necator H16 by testing endogenous and heterologous genes, showing that DIC transporters can support autotrophic growth and higher cell densities.

A five-fold expansion of the global RNA virome reveals multiple new clades of RNA bacteriophages

The paper expands the global RNA virome by five-fold, identifying new clades of RNA bacteriophages and revealing novel virus-host interactions.

Critical Assessment of Metagenome Interpretation - a benchmark of computational metagenomics software

The paper benchmarks computational metagenomics software using complex datasets, showing strengths and limitations in assembly, binning, and taxonomic profiling.