Michelle Ann O'Malley

Engineering anaerobic fungal-bacterial consortia for direct conversion of lignocellulosic biomass into medium-chain fatty acids

This study engineers an anaerobic fungal-bacterial consortium to convert lignocellulosic biomass into medium-chain fatty acids without pretreatment, achieving a 21.0% conversion yield.

The anaerobic fungus Caecomyces churrovis produces H2 via a non-bifurcating NADH-dependent enzyme complex

This paper identifies a non-bifurcating NADH-dependent enzyme complex in anaerobic fungi responsible for H2 production, distinct from ferredoxin-dependent pathways.

CAZyme domain architectures suggest fine-scale functional differentiation among anaerobic fungi and bacteria during lignocellulose conversion to volatile fatty acids

Genomic and Transcriptomic Characterization of Carbohydrate-Active Enzymes in the Anaerobic Fungus Neocallimastix cameroonii var. constans

This paper characterizes the genomic and transcriptomic features of Neocallimastix cameroonii var. constans, an anaerobic fungus, revealing its capacity to degrade lignocellulose and identifying key carbohydrate-active enzymes.

Targeted rRNA depletion enables efficient mRNA sequencing in diverse bacterial species and complex co-cultures

EMBR-seq+ efficiently depletes rRNA in diverse bacterial species and co-cultures, enabling accurate transcriptome analysis of non-model microbial systems.

A five-fold expansion of the global RNA virome reveals multiple new clades of RNA bacteriophages

The paper expands the global RNA virome by five-fold, identifying new clades of RNA bacteriophages and revealing novel virus-host interactions.

Efficient and cost-effective bacterial mRNA sequencing from low input samples through ribosomal RNA depletion

The paper introduces EMBR-seq, a method for efficient and cost-effective bacterial mRNA sequencing by depleting rRNA, enabling deeper transcriptome analysis from low input samples.