Author

Yanlan Cao

Southern University of Science and TechnologyORCID 0000-0002-4237-6749Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Xiaoyan ShiiD· 2 shared Yangyi ZhangiD· 2 shared Yuci Wang· 2 shared Chen CheniD· 1 shared Chih-Hung HsuiD· 1 shared Dian Wang· 1 shared Folan Lin· 1 shared Hao CheniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

Xiaoyan ShiORCID

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3 papers

Recent·Most cited

EOLA1, a novel mitochondria-localized protein critical for heart functions via regulating mitochondrial translation

Xiaoyan Shi, Yangyi Zhang, Nanbo Liu, Ruiqi Wang, Nan Zhang, Yanlan Cao, Dian Wang, Yuxuan Jin, Qingren Meng, Simin Fan, Jia Yao, Chih-Hung Hsu, Shuoji Zhu, Ping Zhu, Yang Shi, Hao Chen

This study identifies EOLA1 as a mitochondrial protein critical for translation and heart function through interactions with 12S mt-rRNA and TUFM.

bioRxiv · Jan 12, 2026 · PreprintMolecular Biology

ZCCHC4 Promotes Translation of Replication-dependent Histone mRNAs by Recruiting Cytoplasmic eIF3 complex

Ruiqi Wang, Xiaoyan Shi, Yangyi Zhang, Yuci Wang, Yanlan Cao, Rui Feng, Chen Chen, Yingchun Zhang, Hao Chen, Honghui Ma

This study shows ZCCHC4 promotes translation of replication-dependent histone mRNAs by interacting with the cytoplasmic eIF3 complex, leading to genomic instability and tumor suppression upon its depletion.

bioRxiv · Jun 21, 2025 · PreprintCancer Biology

Depletion of rRNA Methyltranferase METTL5 Enhances Anti-Tumor Immune Response via Neoantigen Generated from Cryptic Translation

Yangyi Zhang, Xiaoyan Shi, Yuci Wang, Ruiqi Wang, Folan Lin, Yanlan Cao, Wanqiu Li, Hao Chen

This study shows that inhibiting METTL5 increases neoantigen production and enhances anti-tumor immunity through non-canonical translation in murine models.

bioRxiv · Jun 6, 2025 · PreprintCancer Biology