Cancer BiologybioRxivPreprint
ZCCHC4 Promotes Translation of Replication-dependent Histone mRNAs by Recruiting Cytoplasmic eIF3 complex
Ruiqi Wang, Xiaoyan Shi, Yangyi Zhang…·Honghui Ma
This study shows ZCCHC4 promotes translation of replication-dependent histone mRNAs by interacting with the cytoplasmic eIF3 complex, leading to genomic instability and tumor suppression upon its depletion.
DOI 10.1101/2025.06.21.660898