Author
The University of Texas Southwestern Medical CenterORCID 0000-0002-6330-4891Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Yi Jiang, Xiaowei Zhan, Peiran Quan, Ruheng Wang, Fangjiang Wu, Junhui Mi, Jia Yao, Bo Yao, Guanghua Xiao, Wenqi Shi, Yang Xie
SpatialOmicsLab provides an integrated environment with AI tools for spatial transcriptomics analysis, outperforming expert workflows in multiple tasks.
bioRxiv · Oct 8, 2026 · PreprintBioinformatics
Jia Yao, Yuqiu Yang, Y Jiang, Qin Zhou, Ling Cai, Wenqi Shi, Zhikai Chi, Peiran Quan, Munir H. Buhaya, Bo Yao, Gu Xiao, Emina H. Huang, Y D Xie
The paper introduces STORM, a method to identify recurrent spatial motifs in colorectal cancer without cell-type labels, finding a fibroblast barrier linked to immune exclusion and prognosis.
bioRxiv · Jul 15, 2026 · PreprintBioinformatics
Xiaoyan Shi, Yangyi Zhang, Nanbo Liu, Ruiqi Wang, Nan Zhang, Yanlan Cao, Dian Wang, Yuxuan Jin, Qingren Meng, Simin Fan, Jia Yao, Chih-Hung Hsu, Shuoji Zhu, Ping Zhu, Yang Shi, Hao Chen
This study identifies EOLA1 as a mitochondrial protein critical for translation and heart function through interactions with 12S mt-rRNA and TUFM.
bioRxiv · Jan 12, 2026 · PreprintMolecular Biology
Jia Yao, Ji Seon Shim, Kelly Wong, James J. Zhu, Yunhe Liu, Sung Wook Kang, Kelli Bryan M. Burt, Jong Min Choi, Claire Lee, Idania Carolina Lubo Julio, Luisa Maren Solis Soto, Sharia Hernandez, Karen Colbert, Wei Lü, Khaja Khan, , Tao Wang
This study introduces a deep learning model called spacer to analyze spatially resolved transcriptomics data, revealing novel insights into cellular recruitment mechanisms in tumors and heart tissue during myocarditis.
bioRxiv · Nov 20, 2025 · PreprintBioinformatics