Author

Alejandro Villar‐Briones

Okinawa Institute of Science and Technology Graduate UniversityORCID 0000-0002-4246-3877Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 1 Genomics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Akiko YanagiyaiD· 1 shared Andrew W. LiuiD· 1 shared Charles PlessyiD· 1 shared Chihiro Kawano· 1 shared Eisuke HayakawaiD· 1 shared Guillaume VarèsiD· 1 shared Hiroshi WatanabeiD· 1 shared Ivan MbogoiD· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperPhysiology

Akiko YanagiyaORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

A transphyletic study of metazoan β-catenin protein complexes

Ivan Mbogo, Chihiro Kawano, Ryotaro Nakamura, Yuko Tsuchiya, Alejandro Villar‐Briones, Yoshitoshi Hirao, Y. Yasuoka, Eisuke Hayakawa, Kentaro Tomii, Hiroshi Watanabe

This study compares β-catenin sequences and function across nonbilaterian metazoans and Xenopus embryos, revealing conserved structural and functional properties of β-catenin complexes.

Zoological Letters · Dec 2, 2024Peer-reviewedEvolutionary Biology

Post-transcriptional regulation by the CCR4-NOT deadenylase complex maintains redox homeostasis in insulin biosynthesis in mouse pancreatic β cells

Akiko Yanagiya, Patrick N. Stoney, Yuki Tara, Shohei Takaoka, Guillaume Varès, Rei Higa, Nicholas R. Friedman, Alejandro Villar‐Briones, Tadashi S. Yamamoto

The paper shows that CNOT7 deletion in mouse pancreatic β cells reduces insulin content and secretion by impairing proinsulin conversion, through reduced PRDX4 and increased CNOT8 binding to Prdx4 mRNA via MSI2.

bioRxiv · Jun 26, 2024 · PreprintPhysiology

Automated phenol-chloroform extraction of high molecular weight genomic DNA for use in long-read single-molecule sequencing.

Andrew W. Liu, Alejandro Villar‐Briones, Nicholas M. Luscombe, Charles Plessy

This paper describes an automated phenol-chloroform DNA extraction protocol using a robot, achieving high molecular weight DNA suitable for long-read sequencing.

F1000Research · Feb 28, 2022Peer-reviewedGenomics