Author

Reza Saberianfar

University of Toronto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Synthetic Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Sachdev S. SidhuiD· 3 shared Shane MierschiD· 3 shared Alevtina Pavlenco· 2 shared Chao CheniD· 2 shared Daisy W. LeungiD· 2 shared Gaya K. AmarasingheiD· 2 shared Giuseppe NovelliiD· 2 shared Mart UstaviD· 2 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersSynthetic Biology

Sachdev S. SidhuORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Peptide-antibody Fusions Engineered by Phage Display Exhibit Ultrapotent and Broad Neutralization of SARS-CoV-2 Variants

Jonathan M. Labriola, Shane Miersch, Gang Chen, Chao Chen, Alevtina Pavlenco, Reza Saberianfar, Francesca Caccuri, Alberto Zani, Nitin Sharma, Annie Feng, Daisy W. Leung, Arnaldo Caruso, Giuseppe Novelli, Gaya K. Amarasinghe, Sachdev S. Sidhu

This paper describes the engineering of peptide-antibody fusions using phage display to enhance neutralization potency and breadth against SARS-CoV-2 variants.

ACS Chemical Biology · Jun 22, 2022Peer-reviewedSynthetic Biology

Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations

Shane Miersch, Zhijie Li, Reza Saberianfar, Mart Ustav, James Brett Case, Levi L. Blazer, Chao Chen, Wei Ye, Alevtina Pavlenco, Maryna Gorelik, Julia Garcia Perez, Suryasree Subramania, Serena Singh, Lynda Ploder, Safder S. Ganaie, , Sachdev S. Sidhu

This paper develops tetravalent SARS-CoV-2 neutralizing antibodies that are more potent and resistant to escape mutations than bivalent versions.

Journal of Molecular Biology · Jul 28, 2021Peer-reviewedSynthetic Biology

Human ACE2 receptor polymorphisms predict SARS-CoV-2 susceptibility

Kushal Suryamohan, Devan C. Diwanji, Eric W. Stawiski, Ravi Kr Gupta, Shane Miersch, Jiang Liu, Chao Chen, Ying-Ping Jiang, Frédéric A. Fellouse, J. Fah Sathirapongsasuti, Patrick K. Albers, Deepak Tanneeru, Reza Saberianfar, Aakrosh Ratan, Gavin Washburn, , Somasekar Seshagiri

This study identifies ACE2 receptor polymorphisms that may influence susceptibility to SARS-CoV-2 by altering the interaction between ACE2 and the viral S-protein.

Communications Biology · Apr 12, 2021Peer-reviewedGenetics