Small molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: Development of screening assays and insight into GluK3 structure
Yasmin Bay, Raminta Venskutonytė, Stine M. Frantsen, Thor S. Thorsen, Maria Musgaard, Karla Frydenvang, Pierre Francotte, Bernard Pirotte, Philip Charles Biggin, Anders S. Kristensen, Thomas P. Boesen, Darryl S. Pickering, Michael Gajhede, J.S. Kastrup
This study develops screening assays for modulating kainate receptors GluK1-3 and provides structural insights into GluK3's ligand-binding domain.
FEBS Journal · Dec 25, 2023Peer-reviewedNeuroscience