Author

Maria Musgaard

University of OttawaORCID 0000-0001-6096-9014Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Abby Williamson· 1 shared Alexander I.H. SiddiquiiD· 1 shared Anders S. KristenseniD· 1 shared Bernard PirotteiD· 1 shared Charlotte DeaneiD· 1 shared Darryl S. PickeringiD· 1 shared David M. MacLeaniD· 1 shared J.S. KastrupiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperNeuroscience

Abby Williamson

Mutual co-authors in cluster

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3 papers

Recent·Most cited

A framework for testing structural hypotheses of protein dynamics against experimental HDX-MS data

Alexander I.H. Siddiqui, R. Skyner, Maria Musgaard, Srinath Krishnamurthy, Charlotte Deane, Oliver M. Crook

The paper introduces ValDX, a framework to validate and quantify uncertainty in HDX-MS data integration with protein structural ensembles, showing it outperforms conventional metrics in distinguishing correct from incorrect models.

bioRxiv · Mar 4, 2026 · PreprintBiophysics

Small molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: Development of screening assays and insight into GluK3 structure

Yasmin Bay, Raminta Venskutonytė, Stine M. Frantsen, Thor S. Thorsen, Maria Musgaard, Karla Frydenvang, Pierre Francotte, Bernard Pirotte, Philip Charles Biggin, Anders S. Kristensen, Thomas P. Boesen, Darryl S. Pickering, Michael Gajhede, J.S. Kastrup

This study develops screening assays for modulating kainate receptors GluK1-3 and provides structural insights into GluK3's ligand-binding domain.

FEBS Journal · Dec 25, 2023Peer-reviewedNeuroscience

β11-12 linker isomerization governs Acid-sensing ion channel desensitization and recovery

Matthew L. Rook, Abby Williamson, John D. Lueck, Maria Musgaard, David M. MacLean

The paper investigates the role of β11-12 linker isomerization in ASIC desensitization and recovery using electrophysiology, simulations, and cross-linking.

eLife · Feb 7, 2020Peer-reviewedNeuroscience