Vittoria Matafora

This study shows compressive stress activates a calcium-dependent pathway that reduces translation and proteostasis through multiple mechanisms, correlating with poor survival in pancreatic cancer.

This study shows that NUMB's Ex3 exon directs it to the plasma membrane, forming a complex with SNX9 that recruits and transports p53 via exosomes, enabling p53-dependent transcriptional activity in recipient cells.

This study uses proteomics to analyze astrocyte secretome changes in response to soluble Aβ oligomers, identifying dysregulated proteins and potential biomarkers for Alzheimer's disease.

This study uses patient-specific iPSCs to model GLD, revealing cell type-specific disease phenotypes and the importance of GALC restoration for neural differentiation.