Daniel Růžek

The paper reanalyzes sequencing data to reconstruct full-length monkeypox virus transcripts and shows temporal changes in gene regulation and transcript structure.

This study evaluates remdesivir and bemnifosbuvir's efficacy against TBEV in vitro and ex vivo, finding dose-dependent viral load reduction with notable cytotoxicity for remdesivir.

The paper identifies two human monoclonal antibodies that neutralize West Nile virus and related orthoflaviruses, offering potential for antibody-based interventions.

This study shows tattoo ink causes long-term inflammation in lymph nodes and reduces vaccine efficacy against COVID-19.

This paper introduces a dual neutralisation assay for SARS-CoV-2 and influenza viruses, demonstrating its sensitivity and specificity in detecting neutralising antibodies.

This study investigates how structural proteins of TBEV influence viral tropism by comparing a chimeric virus with low-pathogenic LGTV and TBEV using structural and imaging analyses.

This study shows HSV-1 infection induces Aβ clustering and neurodegeneration pathways in iPSC-derived neurons, supporting the pathogen infection hypothesis for Alzheimer's disease.

This study examines long-term immune changes post-COVID-19 and the impact of BCG vaccination and latent infections on disease severity.

This study uses CAGE and long-read RNA sequencing to analyze the transcriptional architecture of human monkeypox virus, identifying alternative TSSs, TESs, promoter elements, and novel genes.

This study shows that enhanced RNAi in mice does not improve antiviral immunity in vivo, but may work in vitro under specific conditions.