Michael D. Carver

Septins regulate cytokinesis and multicellular development in the closest living relatives of animals

This study shows that septins regulate cytokinesis and multicellular development in Salpingoeca rosetta, a choanoflagellate closely related to animals.

Glk1p is an actin fold metabolic enzyme whose polymerization is sensitive to nucleotide state

This study identifies glucose 6-phosphate (G6P) as a second trigger for Glk1p polymerization and shows that ADP causes filament disassembly, linking metabolic state to enzyme polymerization.

A Role for Cross-linking Proteins in Actin Filament Network Organization and Force Generation

The paper investigates the role of actin filament crosslinking proteins in force generation during clathrin-mediated endocytosis in yeast, showing that increased crosslinking enhances internalization under high turgor pressure.